DLG3 antibody (AA 749-817)

Catalog No. ABIN5518907

Product Details anti-DLG3 Antibody

Target: DLG3 (Discs, Large Homolog 3 (DLG3))

Binding Specificity: AA 749-817

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLG3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Disks large homolog 3(DLG3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Cross-Reactivity (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Disks large homolog 3(DLG3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: discs large MAGUK scaffold protein 3
Protein Name: Disks large homolog 3

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human SAP102 recombinant protein (Position: E749-L817). Human SAP102 shares 98.6% amino acid (aa) sequence identity with both mouse and rat SAP102.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for DLG3

Target: DLG3 (Discs, Large Homolog 3 (DLG3))

Alternative Name: DLG3 (DLG3 Products)

Synonyms: MRX antibody, MRX90 antibody, NEDLG antibody, SAP102 antibody, XLMR antibody, DLG3 antibody, fa66c08 antibody, fa66e02 antibody, fd02c12 antibody, fu95c12 antibody, im:7138640 antibody, si:ch211-276g21.1 antibody, wu:fa66c08 antibody, wu:fa66e02 antibody, wu:fd02c12 antibody, wu:fu95c12 antibody, Dlgh3 antibody, mKIAA1232 antibody, MPP3 antibody, 6430514B01 antibody, CSG18 antibody, Dlg3 antibody, Dusp3 antibody, discs large MAGUK scaffold protein 3 antibody, membrane palmitoylated protein 3 antibody, discs, large homolog 3 (Drosophila) antibody, membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) antibody, DLG3 antibody, MPP3 antibody, dlg3 antibody, Dlg3 antibody, Mpp3 antibody

Background: Disks large homolog 3 (DLG3) also known as neuroendocrine-DLG or synapse-associated protein 102 (SAP-102) is a protein that in humans is encoded by the DLG3 gene. DLG3 is a member of the membrane-associated guanylate kinase (MAGUK) superfamily of proteins. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked mental retardation.

Synonyms: Disks large homolog 3, Neuroendocrine-DLG, Synapse-associated protein 102, SAP-102, SAP102, XLMR, DLG3, KIAA1232

Gene ID: 1741

UniProt: Q92796