PPIA antibody (AA 116-165)

Catalog No. ABIN5518864

Product Details anti-PPIA Antibody

Target: PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

Binding Specificity: AA 116-165

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPIA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Peptidyl-prolyl cis-trans isomerase A(PPIA) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Peptidyl-prolyl cis-trans isomerase A(PPIA) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: peptidylprolyl isomerase A (cyclophilin A)
Protein Name: Peptidyl-prolyl cis-trans isomerase A

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Cyclophilin A recombinant protein (Position: T116-E165). Human Cyclophilin A shares 98% and 95.9% amino acid (aa) sequence identity with mouse and rat Cyclophilin A, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for PPIA

Target: PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

Alternative Name: PPIA (PPIA Products)

Synonyms: Cyp1 antibody, PPIA-2 antibody, fa93g09 antibody, ppia antibody, wu:fa93g09 antibody, wu:fb05e11 antibody, wu:fb13h02 antibody, wu:fb15a05 antibody, CYPA antibody, CypA antibody, Cypa antibody, CYPH antibody, CYCA antibody, CyP-A antibody, MGC75715 antibody, 2700098C05 antibody, Cphn antibody, CyP-18 antibody, MT-ND1 antibody, MTND1 antibody, NADH1 antibody, ND1 antibody, cypA antibody, PPIase A antibody, ppial antibody, wu:fj18g05 antibody, zgc:73102 antibody, zgc:86688 antibody, peptidylprolyl isomerase A antibody, peptidylprolyl isomerase Aa (cyclophilin A) antibody, peptidylprolyl isomerase A (cyclophilin A) L homeolog antibody, cyclophilin A antibody, cyclophilin a antibody, peptidylprolyl isomerase A (cyclophilin A) antibody, peptidylprolyl isomerase Ab (cyclophilin A) antibody, PPIA antibody, ppiaa antibody, ppia.L antibody, Cypa antibody, CNB01230 antibody, CNB01290 antibody, Tc00.1047053506925.300 antibody, Tb11.03.0250 antibody, CYPA antibody, Ppia antibody, ppia antibody, ppiab antibody

Background: Cyclophilin A (PPIA), Peptidylprolyl isomerase A, is an enzyme that in humans is encoded by the PPIA gene. Using chromosome 7 and chromosome 10 deletion hybrid panels, the PPIA coding gene is localized to 7p13-p11.2. This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. Cyclophilin A is also a member of the immunophilin class of proteins that all possess peptidyl-prolyl cis/trans isomerase activity and are believed to be involved in protein folding and/or intracellular protein transport. And Cyclophilin A binds to the Gag protein of human immunodeficiency virus type 1 (HIV-1). Additionally, Cyclophilin A may have an essential function in HIV-1 replication.may have an essential function in HIV-1 replication.

Synonyms: Cyclophilin A | CyclophilinA | CYPA | CYPH | HEL S 69p | PPIA | PPIase A | Rotamase A | RotamaseA | P62937

Gene ID: 5478

UniProt: P62937