LGALS1/Galectin 1 antibody (AA 2-135)

Catalog No. ABIN5518716

Product Details anti-LGALS1/Galectin 1 Antibody

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Binding Specificity: AA 2-135

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LGALS1/Galectin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Galectin-1(LGALS1) detection. Tested with WB, IHC-P, ELISA in Human,Mouse,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Galectin-1(LGALS1) detection. Tested with WB, IHC-P, ELISA in Human,Mouse,Rat.
Gene Name: UPF3 regulator of nonsense transcripts homolog B (yeast)
Protein Name: Galectin-1

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Galectin 1 recombinant protein (Position: A2-D135). Human Galectin 1 shares 88% and 90% amino acid (aa) sequence identity with mouse and rat Galectin 1, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human

Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for LGALS1/Galectin 1

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Alternative Name: LGALS1 (LGALS1 Products)

Synonyms: GAL1 antibody, GBP antibody, Galectin-1 antibody, LGAS1 antibody, LGALS1 antibody, MGC64502 antibody, GB10026 antibody, AA410090 antibody, Gal-1 antibody, Galbp antibody, L-14.5 antibody, L14 antibody, Lect14 antibody, galectin-1 antibody, Galaptin antibody, galectin 1 antibody, galectin-1 antibody, lectin, galactoside-binding, soluble, 1 L homeolog antibody, protein enabled antibody, lectin, galactose binding, soluble 1 antibody, LGALS1 antibody, Lgals1 antibody, CC1G_05003 antibody, CC1G_05004 antibody, lgals1.L antibody, LOC408848 antibody

Background: Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-1 may act as an autocrine negative growth factor that regulates cell proliferation. Galectin-1 expression in Hodgkin Lymphoma has also been shown to mediate immunosuppression of CD8+ T-cells. It is thought to play a role in creating immune tolerance in pregnancy. It has been found that Galectin-1-mediated production of IL6 may assist in augmenting the innate immune response against NiV. Galectin-1 may also be a significant factor that augments the efficiency of the HIV-1 infection process.

Synonyms: 14 kDa laminin-binding protein antibody|14 kDa lectin antibody|Beta galactoside binding lectin antibody|Beta galactoside binding lectin L 14 I antibody|beta galactoside binding protein antibody|Beta-galactoside-binding lectin L-14-I antibody|DKFZp686E23103 antibody|Gal 1 antibody|Gal-1 antibody|GAL1 antibody|Galaptin antibody|Galbp antibody|Galectin antibody|Galectin-1 antibody|Galectin1 antibody|GBP antibody|HBL antibody|HLBP14 antibody|HPL antibody|L 14.5 antibody|L-14.5 antibody|L14 antibody|Lactose binding lectin 1 antibody|Lactose-binding lectin 1 antibody|Lect14 antibody|Lectin galactoside binding soluble 1 antibody|Lectin galactoside-binding soluble 1 antibody|LEG1_HUMAN antibody|LGALS 1 antibody|LGALS1 antibody|Lgals1 lectin galactose binding soluble 1 antibody|MAPK activating protein MP12 antibody|Putative MAPK activating protein MP12 antibody|Putative MAPK-activating protein PM12 antibody|S Lac lectin 1 antibody|S-Lac lectin 1 antibody

Gene ID: 3956

UniProt: P09382

Pathways: Carbohydrate Homeostasis