Proteoglycan 4 antibody (N-Term)

Catalog No. ABIN5518064

Product Details anti-Proteoglycan 4 Antibody

Target: Proteoglycan 4 (PRG4)

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Proteoglycan 4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KIKSSKNSAA NRELQKKLKV KDNKKNRTKK KPTPKPPVVD EAGSGLDNGD

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PRG4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Proteoglycan 4

Target: Proteoglycan 4 (PRG4)

Alternative Name: PRG4 (PRG4 Products)

Synonyms: CACP antibody, HAPO antibody, JCAP antibody, MSF antibody, SZP antibody, bG174L6.2 antibody, lubricin antibody, prg4 antibody, si:dkey-97o5.3 antibody, zgc:122988 antibody, PRG4 antibody, DOL54 antibody, proteoglycan 4 antibody, proteoglycan 4b antibody, proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein) antibody, PRG4 antibody, Prg4 antibody, prg4b antibody

Background: The protein encoded by this gene is a large proteoglycan that is synthesized by chondrocytes located at the surface of articular cartilage and by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Alternative splicing results in multiple transcript variants.

Alias Symbols: MSF, SZP, CACP, HAPO, JCAP

Protein Size: 853

Gene ID: 10216

NCBI Accession: NP_001121180

UniProt: J3KP74