DCAF12L2 antibody (C-Term)

Catalog No. ABIN5518006

Product Details anti-DCAF12L2 Antibody

Target: DCAF12L2 (DDB1 and CUL4 Associated Factor 12-Like 2 (DCAF12L2))

Binding Specificity: C-Term

Reactivity: Human, Dog, Pig, Rabbit, Guinea Pig, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCAF12L2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LDPRQRQQNI RPLCSREGGT GVRSLSFYQH IITVGTGHGS LLFYDIRAQK

Predicted Reactivity: Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against DCAF12L2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DCAF12L2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DCAF12L2

Target: DCAF12L2 (DDB1 and CUL4 Associated Factor 12-Like 2 (DCAF12L2))

Alternative Name: DCAF12L2 (DCAF12L2 Products)

Background: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD), which may facilitate formation of heterotrimeric or multi-protein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene appears to represent an intronless retrocopy of a related multi-exon gene located on chromosome 9. However, the CDS of this intronless gene remains intact, it is conserved in other mammalian species, it is known to be transcribed, and it is therefore thought to encode a functional protein.

Alias Symbols: WDR40C

Protein Interaction Partner: COPS6, CUL4A,

Protein Size: 463

Gene ID: 340578

NCBI Accession: NM_001013628, NP_001013650

UniProt: Q5VW00