CFHR3 antibody (Middle Region)

Catalog No. ABIN5517788

Product Details anti-CFHR3 Antibody

Target: CFHR3 (Complement Factor H-Related 3 (CFHR3))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CFHR3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FISESSSIYI LNKEIQYKCK PGYATADGNS SGSITCLQNG WSAQPICINS

Predicted Reactivity: Horse: 79%, Human: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against FHR3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human FHR3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CFHR3

Target: CFHR3 (Complement Factor H-Related 3 (CFHR3))

Alternative Name: FHR3 (CFHR3 Products)

Synonyms: EG624286 antibody, CFHL3 antibody, DOWN16 antibody, FHR-3 antibody, FHR3 antibody, HLF4 antibody, complement factor H-related 3 antibody, complement factor H related 3 antibody, Cfhr3 antibody, CFHR3 antibody

Background: The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: CFHR3, CFHL3, FHR3,

Protein Interaction Partner: PRDX4, C3,

Protein Size: 330

Gene ID: 10878

NCBI Accession: NP_066303

UniProt: Q02985