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PJA1 antibody (Middle Region)
PJA1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PJA1 Antibody
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Target
See all PJA1 Antibodies
PJA1
(Praja Ring Finger 1, E3 Ubiquitin Protein Ligase (PJA1))
Binding Specificity
All epitopes for PJA1 antibodies
Middle Region
Reactivity
All reactivities for PJA1 antibodies
Human
Host
All hosts for PJA1 antibodies
Rabbit
Clonality
All clonalities for PJA1 antibodies
Polyclonal
Conjugate
All conjugates for PJA1 antibodies
This PJA1 antibody is un-conjugated
Application
All applications for PJA1 antibodies
Western Blotting (WB)
Sequence
MQPGVFMLDG NNNLEDDSSV SEDLEVDWSL FDGFADGLGV AEAISYVDPQ
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human PJA1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 16 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for PJA1
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Target
PJA1
(Praja Ring Finger 1, E3 Ubiquitin Protein Ligase (PJA1))
Alternative Name
PJA1 (PJA1 Products )
Synonyms
PRAJA1 antibody, RNF70 antibody, praja ring finger ubiquitin ligase 1 antibody, PJA1 antibody, Pja1 antibody
Background
This gene encodes an enzyme that has E2-dependent E3 ubiquitin-protein ligase activity. This enzyme belongs to a class of ubiquitin ligases that include a RING finger motif, and it can interact with the E2 ubiquitin-conjugating enzyme UbcH5B. This gene is located in an area of chromosome X where several X-linked mental retardation disorders have been associated, and it has also been found as part of a contiguous gene deletion associated with craniofrontonasal syndrome, though a direct link to any disorder has yet to be demonstrated. Alternative splicing results in multiple transcript variants. Alias Symbols: RNF70, PRAJA1 Protein Size: 643
Gene ID
64219
NCBI Accession
NM_001032396 , NP_001027568
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