OLFML3 antibody (N-Term)

Catalog No. ABIN5517620

Product Details anti-OLFML3 Antibody

Target: OLFML3 (Olfactomedin-Like 3 (OLFML3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OLFML3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: WSGPLQGQQH HLVEYMERRL AALEERLAQC QDQSSRHAAE LRDFKNKMLP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against OLFML3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human OLFML3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for OLFML3

Target: OLFML3 (Olfactomedin-Like 3 (OLFML3))

Alternative Name: OLFML3 (OLFML3 Products)

Synonyms: HNOEL-iso antibody, OLF44 antibody, 2810002E22Rik antibody, AI115209 antibody, AW550633 antibody, ONT3 antibody, mONT3 antibody, ONT1 antibody, ont1 antibody, olfml3 antibody, olfml3a antibody, wu:faa48g10 antibody, wu:fb02c05 antibody, wu:fl19d05 antibody, zgc:153815 antibody, olf44 antibody, MGC145952 antibody, hnoel-iso antibody, olfml3b antibody, zgc:153761 antibody, olfactomedin like 3 antibody, olfactomedin-like 3 antibody, olfactomedin like 3 L homeolog antibody, olfactomedin-like 3b antibody, olfactomedin-like 3a antibody, OLFML3 antibody, Olfml3 antibody, olfml3.L antibody, olfml3b antibody, olfml3 antibody, olfml3a antibody

Background: OLFML3 is a secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. It stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation. It may have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes.

Alias Symbols: OLFML3, PSEC0035, PSEC0173, PSEC0244, UNQ663/PRO1294,

Protein Interaction Partner: Dlg4, MYOC, FEZ1, HSPB3, SETDB1, CKMT2,

Protein Size: 406

Gene ID: 56944

NCBI Accession: NP_064575

UniProt: Q9NRN5