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VAC14 antibody (C-Term)
VAC14
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-VAC14 Antibody
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Target
See all VAC14 Antibodies
VAC14
(Vac14 Homolog (VAC14))
Binding Specificity
All epitopes for VAC14 antibodies
C-Term
Reactivity
All reactivities for VAC14 antibodies
Human
Host
All hosts for VAC14 antibodies
Rabbit
Clonality
All clonalities for VAC14 antibodies
Polyclonal
Conjugate
All conjugates for VAC14 antibodies
This VAC14 antibody is un-conjugated
Application
All applications for VAC14 antibodies
Western Blotting (WB)
Sequence
LKDLEVLAEI ASSPAGQTDD PGPLDGPDLQ ASHSELQVPT PGRAGLLNTS
Characteristics
This is a rabbit polyclonal antibody against VAC14. It was validated on Western Blot.
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human VAC14
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for VAC14
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Target
VAC14
(Vac14 Homolog (VAC14))
Alternative Name
VAC14 (VAC14 Products )
Synonyms
ArPIKfyve antibody, TAX1BP2 antibody, TRX antibody, AA959718 antibody, BC032215 antibody, D8Wsu151e antibody, Tax1bp2 antibody, Trx antibody, ingls antibody, Vac14 homolog L homeolog antibody, Vac14, PIKFYVE complex component antibody, Vac14 homolog (S. cerevisiae) antibody, vac14.L antibody, VAC14 antibody, Vac14 antibody
Background
The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns(3,5)P2 phosphatase FIG4 (MIM 609390). VAC14 functions as an activator of PIKFYVE. Alias Symbols: TAX1BP2, TRX Protein Size: 782
Gene ID
55697
NCBI Accession
NP_060522
UniProt
Q08AM6
Pathways
Inositol Metabolic Process
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