SRGAP2 antibody (N-Term)

Catalog No. ABIN5517501

Product Details anti-SRGAP2 Antibody

Target: SRGAP2 (SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRGAP2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AERFLAKTCS TKDQQFKKDQ NVLSPVNCWN LLLNQVKRES RDHTTLSDIY

Predicted Reactivity: Cow: 87%, Dog: 100%, Guinea Pig: 87%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 87%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SRGAP2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SRGAP2

Target: SRGAP2 (SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2))

Alternative Name: SRGAP2 (SRGAP2 Products)

Synonyms: ARHGAP34 antibody, FNBP2 antibody, SRGAP2A antibody, SRGAP3 antibody, 9930124L22Rik antibody, AI448945 antibody, FBP2 antibody, Fnbp2 antibody, srGAP3 antibody, AI452337 antibody, Arhgap14 antibody, D130026O08Rik antibody, Gbi antibody, MEGAP antibody, WRP antibody, mKIAA0411 antibody, RGD1566016 antibody, srGAP2 antibody, srgap2a antibody, wu:fb47h12 antibody, zgc:136814 antibody, fnbp2 antibody, srgap2 antibody, SLIT-ROBO Rho GTPase activating protein 2 antibody, SLIT-ROBO Rho GTPase activating protein 3 antibody, SLIT-ROBO Rho GTPase activating protein 2 L homeolog antibody, SRGAP2 antibody, Srgap2 antibody, Srgap3 antibody, srgap2 antibody, srgap2.L antibody

Background: This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus.

Alias Symbols: FNBP2, SRGAP3, SRGAP2A, ARHGAP34

Protein Interaction Partner: UBC, PPP2R1A, YWHAB, YWHAE, UBD, FASLG, HERC2, EXOC1, DISC1, YWHAG, MYO1G, YLPM1, ATAD3A, ITSN2, SLC25A12, WIPF1, WAS, DIAPH1, ROBO1,

Protein Size: 459

Gene ID: 23380

NCBI Accession: NM_001170637, NP_001258799

UniProt: P0DJJ0