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TXNDC12 antibody (N-Term)
TXNDC12
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TXNDC12 Antibody
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Target
See all TXNDC12 Antibodies
TXNDC12
(Thioredoxin Domain Containing 12 (Endoplasmic Reticulum) (TXNDC12))
Binding Specificity
All epitopes for TXNDC12 antibodies
N-Term
Reactivity
All reactivities for TXNDC12 antibodies
Human
Host
All hosts for TXNDC12 antibodies
Rabbit
Clonality
All clonalities for TXNDC12 antibodies
Polyclonal
Conjugate
All conjugates for TXNDC12 antibodies
This TXNDC12 antibody is un-conjugated
Application
All applications for TXNDC12 antibodies
Western Blotting (WB)
Sequence
METRPRLGAT CLLGFSFLLL VISSDGHNGL GKGFGDHIHW RTLEDGKKEA
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human TXNDC12
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for TXNDC12
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Target
TXNDC12
(Thioredoxin Domain Containing 12 (Endoplasmic Reticulum) (TXNDC12))
Alternative Name
TXNDC12 (TXNDC12 Products )
Synonyms
AG1 antibody, AGR1 antibody, ERP16 antibody, ERP18 antibody, ERP19 antibody, PDIA16 antibody, TLP19 antibody, hAG-1 antibody, hTLP19 antibody, 0610040B21Rik antibody, ERp16 antibody, ERp19 antibody, RGD1305960 antibody, thioredoxin domain containing 12 antibody, thioredoxin domain containing 12 (endoplasmic reticulum) antibody, TXNDC12 antibody, Txndc12 antibody
Background
This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants. Alias Symbols: AG1, AGR1, ERP16, ERP18, ERP19, TLP19, hAG-1, PDIA16, hTLP19 Protein Size: 172
Gene ID
51060
NCBI Accession
NM_015913 , NP_056997
UniProt
O95881
Pathways
Cell RedoxHomeostasis
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