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ORC4 antibody (C-Term)
ORC4
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ORC4 Antibody
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Target
See all ORC4 Antibodies
ORC4
(Origin Recognition Complex, Subunit 4 (ORC4))
Binding Specificity
All epitopes for ORC4 antibodies
C-Term
Reactivity
All reactivities for ORC4 antibodies
Human
Host
All hosts for ORC4 antibodies
Rabbit
Clonality
All clonalities for ORC4 antibodies
Polyclonal
Conjugate
All conjugates for ORC4 antibodies
This ORC4 antibody is un-conjugated
Application
All applications for ORC4 antibodies
Western Blotting (WB)
Sequence
IIAMKHLNDI YEEEPFNFQM VYNEFQKFVQ RKAHSVYNFE KPVVMKAFEH
Characteristics
This is a rabbit polyclonal antibody against ORC4. It was validated on Western Blot.
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human ORC4
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for ORC4
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Target
ORC4
(Origin Recognition Complex, Subunit 4 (ORC4))
Alternative Name
ORC4 (ORC4 Products )
Synonyms
ORC4L antibody, ORC4P antibody, Orc4P antibody, Orc4l antibody, mMmORC4 antibody, CG2917 antibody, DmORC4 antibody, Dmel\\CG2917 antibody, ORC antibody, ORC4 antibody, dmOrc4 antibody, orc4 antibody, rDmORC antibody, orc4l antibody, fc50c03 antibody, wu:fc50c03 antibody, zgc:85772 antibody, ATORC4 antibody, F23H14.9 antibody, F23H14_9 antibody, ORIGIN RECOGNITION COMPLEX SUBUNIT 4 antibody, origin recognition complex subunit 4 antibody, origin recognition complex subunit 4 antibody, origin recognition complex, subunit 4 antibody, Origin recognition complex subunit 4 antibody, origin recognition complex subunit 4 L homeolog antibody, origin recognition complex subunit Orc4 antibody, ORC4 antibody, Orc4 antibody, orc4.L antibody, orc4 antibody, CNM01830 antibody
Background
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene. Alias Symbols: ORC4, ORC4L, Protein Interaction Partner: RRM2B, TCF4, MCM3, MTUS1, MCM10, FBXL8, FBXO6, FBXO25, FBXL5, ORC3, ORC6, UBC, ORC5, ORC2, MLH1, MCM7, KPNA1, CTBP1, CDKN2A, CCND1, APP, XRCC5, XRCC6, CCL2, tat, MCM2, ORC1, MCM6, MCM4, DBF4, RPA2, Protein Size: 436
Gene ID
5000
UniProt
O43929
Pathways
Mitotic G1-G1/S Phases , DNA Replication , Synthesis of DNA
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