FBXL15 antibody (N-Term)
FBXL15
Reactivity: Human, Mouse, Rabbit, Rat, Cow, Dog, Goat, Horse
WB
Host: Rabbit
Polyclonal
unconjugated
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- Target See all FBXL15 Antibodies
- FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))
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Binding Specificity
- N-Term
- Reactivity
- Human, Mouse, Rabbit, Rat, Cow, Dog, Goat, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FBXL15 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PPMEPSGGEQ EPGAVRFLDL PWEDVLLPHV LNRVPLRQLL RLQRVSRAFR
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Goat: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against FBXL15. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human FBXL15
- Top Product
- Discover our top product FBXL15 Primary Antibody
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anti-F-Box and Leucine-Rich Repeat Protein 15 (FBXL15) (AA 252-280), (C-Term) antibody
FBXL15 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB26324 unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))
- Alternative Name
- FBXL15 (FBXL15 Products)
- Background
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FBXL15 is a substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. It is required for dorsal/ventral pattern formation and bone mass maintenance and also mediates ubiquitination of SMURF2 and WWP2.
Alias Symbols: FBXO37, Fbl15, JET, PSD
Protein Interaction Partner: HNRNPD, SKP1, ITCH, SMURF2, HECW2, SMURF1, NEDD4L, HECW1, WWP2, WWP1, RBX1, CUL1, NEDD4, HSP90AA1, COPS6, UBC,
Protein Size: 300 - Gene ID
- 79176
- NCBI Accession
- NM_024326, NP_077302
- UniProt
- Q9H469
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