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FBXL15 antibody (N-Term)

FBXL15 Reactivity: Human, Cow, Dog, Goat, Horse, Mouse, Rabbit, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5517039
  • Target See all FBXL15 Antibodies
    FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))
    Binding Specificity
    • 7
    • 7
    • 6
    N-Term
    Reactivity
    Human, Cow, Dog, Goat, Horse, Mouse, Rabbit, Rat
    Host
    • 14
    Rabbit
    Clonality
    • 14
    Polyclonal
    Conjugate
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    This FBXL15 antibody is un-conjugated
    Application
    • 14
    • 13
    • 12
    • 1
    Western Blotting (WB)
    Sequence
    PPMEPSGGEQ EPGAVRFLDL PWEDVLLPHV LNRVPLRQLL RLQRVSRAFR
    Predicted Reactivity
    Cow: 93%, Dog: 100%, Goat: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against FBXL15. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human FBXL15
    Top Product
    Discover our top product FBXL15 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))
    Alternative Name
    FBXL15 (FBXL15 Products)
    Synonyms
    0710008C12Rik antibody, Fbxo37 antibody, RGD1306444 antibody, fbl15 antibody, fbxo37 antibody, FBXO37 antibody, Fbl15 antibody, JET antibody, PSD antibody, F4I10.140 antibody, F4I10_140 antibody, SLOW MOTION antibody, fbxl15 antibody, zgc:85882 antibody, F-box and leucine-rich repeat protein 15 antibody, F-box and leucine-rich repeat protein 15 L homeolog antibody, F-box and leucine rich repeat protein 15 antibody, F-box family protein antibody, F-box only protein 37 antibody, Fbxl15 antibody, fbxl15.L antibody, FBXL15 antibody, fbxl15 antibody, SLOMO antibody, fbx37 antibody
    Background
    FBXL15 is a substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. It is required for dorsal/ventral pattern formation and bone mass maintenance and also mediates ubiquitination of SMURF2 and WWP2.

    Alias Symbols: FBXO37, Fbl15, JET, PSD

    Protein Interaction Partner: HNRNPD, SKP1, ITCH, SMURF2, HECW2, SMURF1, NEDD4L, HECW1, WWP2, WWP1, RBX1, CUL1, NEDD4, HSP90AA1, COPS6, UBC,

    Protein Size: 300
    Gene ID
    79176
    NCBI Accession
    NM_024326, NP_077302
    UniProt
    Q9H469
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