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GLDC antibody (C-Term)
GLDC
Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-GLDC Antibody
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Target
See all GLDC Antibodies
GLDC
(Glycine Dehydrogenase (GLDC))
Binding Specificity
All epitopes for GLDC antibodies
C-Term
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
Host
All hosts for GLDC antibodies
Rabbit
Clonality
All clonalities for GLDC antibodies
Polyclonal
Conjugate
All conjugates for GLDC antibodies
This GLDC antibody is un-conjugated
Application
All applications for GLDC antibodies
Western Blotting (WB)
Sequence
ANIEAVDVAK RLQDYGFHAP TMSWPVAGTL MVEPTESEDK AELDRFCDAM
Predicted Reactivity
Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Characteristics
This is a rabbit polyclonal antibody against GCSP. It was validated on Western Blot.
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human GCSP
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for GLDC
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Target
GLDC
(Glycine Dehydrogenase (GLDC))
Alternative Name
GCSP (GLDC Products )
Synonyms
PSPTO1276 antibody, Tb07.43M14.350 antibody, DDBDRAFT_0219205 antibody, DDBDRAFT_0231130 antibody, DDB_0219205 antibody, DDB_0231130 antibody, D030049L12Rik antibody, D19Wsu57e antibody, GCE antibody, GCSP antibody, HYGN1 antibody, fb23b05 antibody, wu:fb23b05 antibody, zgc:66198 antibody, gldc antibody, glycine dehydrogenase (decarboxylating) GcvP antibody, glycine dehydrogenase antibody, glycine cleavage system P-protein antibody, glycine decarboxylase antibody, glycine dehydrogenase (decarboxylating) antibody, glycine decarboxylase S homeolog antibody, gcvP antibody, Tb927.7.1910 antibody, Gldc antibody, GLDC antibody, gldc antibody, gldc.S antibody
Background
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Alias Symbols: GLDC, GCSP, Protein Interaction Partner: SUZ12, UBC, CUL2, TNFAIP3, TLR10, GLDC, Protein Size: 1020
Gene ID
2731
NCBI Accession
NP_000161
UniProt
P23378
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