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GLRB antibody (N-Term)
GLRB
Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Rabbit, Guinea Pig, Horse
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-GLRB Antibody
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Target
See all GLRB Antibodies
GLRB
(Glycine Receptor, beta (GLRB))
Binding Specificity
All epitopes for GLRB antibodies
N-Term
Reactivity
Human, Mouse, Rat, Cow, Pig, Dog, Rabbit, Guinea Pig, Horse
Host
All hosts for GLRB antibodies
Rabbit
Clonality
All clonalities for GLRB antibodies
Polyclonal
Conjugate
All conjugates for GLRB antibodies
This GLRB antibody is un-conjugated
Application
All applications for GLRB antibodies
Western Blotting (WB)
Sequence
LLTTAFLILI SLWVEEAYSK EKSSKKGKGK KKQYLCPSQQ SAEDLARVPA
Predicted Reactivity
Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 100%, Rabbit: 100%, Rat: 100%
Characteristics
This is a rabbit polyclonal antibody against GLRB. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human GLRB
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Discover our top product GLRB Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for GLRB
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Target
GLRB
(Glycine Receptor, beta (GLRB))
Alternative Name
GLRB (GLRB Products )
Synonyms
HKPX2 antibody, glrb antibody, MGC145156 antibody, AI853901 antibody, Glyrb antibody, spa antibody, spastic antibody, glrb2 antibody, zgc:101041 antibody, glycine receptor beta antibody, glycine receptor, beta antibody, glycine receptor, beta subunit antibody, glycine receptor, beta b antibody, GLRB antibody, Glrb antibody, glrb antibody, glrbb antibody
Background
This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. Alias Symbols: GLRB, Protein Interaction Partner: GPHN, Protein Size: 497
Gene ID
2743
UniProt
P48167
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