FBXO6 antibody (N-Term)

Catalog No. ABIN5516720

Product Details anti-FBXO6 Antibody

Target: FBXO6 (F-Box Protein 6 (FBXO6))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HSKAALDSIN ELPENILLEL FTHVPARQLL LNCRLVCSLW RDLIDLMTLW

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FBXO6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO6

Target: FBXO6 (F-Box Protein 6 (FBXO6))

Alternative Name: FBXO6 (FBXO6 Products)

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle.

Alias Symbols: FBG2, FBS2, FBX6, Fbx6b,

Protein Size: 255

Gene ID: 26270

NCBI Accession: NM_001014765, NP_060908

UniProt: Q9H4M3