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RASA4 antibody (Middle Region)
RASA4
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-RASA4 Antibody
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Target
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RASA4
(RAS P21 Protein Activator 4 (RASA4))
Binding Specificity
All epitopes for RASA4 antibodies
Middle Region
Reactivity
All reactivities for RASA4 antibodies
Human
Host
All hosts for RASA4 antibodies
Rabbit
Clonality
All clonalities for RASA4 antibodies
Polyclonal
Conjugate
All conjugates for RASA4 antibodies
This RASA4 antibody is un-conjugated
Application
All applications for RASA4 antibodies
Western Blotting (WB)
Sequence
EEGWFRLQPD QSKSRRHDEG NLGSLQLEVR LRDETVLPSS YYQPLVHLLC
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human RASA4
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 16 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for RASA4
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Target
RASA4
(RAS P21 Protein Activator 4 (RASA4))
Alternative Name
RASA4 (RASA4 Products )
Synonyms
CAPRI antibody, GAPL antibody, AA793972 antibody, AW112107 antibody, BB079060 antibody, mKIAA0538 antibody, RAS p21 protein activator 4 antibody, RASA4 antibody, Rasa4 antibody
Background
This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. Alias Symbols: GAPL, CAPRI, Protein Size: 803
Gene ID
10156
NCBI Accession
NM_001079877 , NP_001073346
UniProt
O43374
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