HLCS antibody (C-Term)

Catalog No. ABIN5516597

Product Details anti-HLCS Antibody

Target: HLCS (Biotin-Protein Ligase (HLCS))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HLCS antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MSVAVVEAVR SIPEYQDINL RVKWPNDIYY SDLMKIGGVL VNSTLMGETF

Characteristics: This is a rabbit polyclonal antibody against BPL1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen for Anti-HLCS antibody is: synthetic peptide directed towards the C-terminal region of Human BPL1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HLCS

Target: HLCS (Biotin-Protein Ligase (HLCS))

Alternative Name: HLCS (HLCS Products)

Synonyms: 410I21.SP6 antibody, D16Jhu34 antibody, HCS antibody, RGD1565360 antibody, holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase) antibody, holocarboxylase synthetase antibody, Hlcs antibody, HLCS antibody

Background: This gene encodes an enzyme that catalyzes the binding of biotin to carboxylases and histones. The protein plays an important role in gluconeogenesis, fatty acid synthesis and branched chain amino acid catabolism. Defects in this gene are the cause of holocarboxylase synthetase deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Alias Symbols: HCS

Protein Size: 726

Gene ID: 3141

NCBI Accession: XP_006724059

UniProt: P50747