NOTO antibody (C-Term)

Catalog No. ABIN5516360

Product Details anti-NOTO Antibody

Target: NOTO (Notochord Homeobox (NOTO))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOTO antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: CSGLWAFPDW APTEDLQDTE RQQKRVRTMF NLEQLEELEK VFAKQHNLVG

Characteristics: This is a rabbit polyclonal antibody against NOTO. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human NOTO

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NOTO

Target: NOTO (Notochord Homeobox (NOTO))

Alternative Name: NOTO (NOTO Products)

Synonyms: Xnot-2 antibody, Xnot2 antibody, not antibody, nota antibody, noto antibody, RGD1562910 antibody, Xnot antibody, Flh antibody, MmNot antibody, Not antibody, tc antibody, Znot antibody, flh antibody, notochord homeobox antibody, notochord homeobox S homeolog antibody, NOTO antibody, not.S antibody, Noto antibody, not antibody, noto antibody

Background: NOTO is a transcription regulator acting downstream of both FOXA2 and T during notochord development. It is required for node morphogenesis. It is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning, it acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function. And it plays a role in regulating axial versus paraxial cell fate (By similarity).

Alias Symbols: NOTO,

Protein Size: 251

Gene ID: 344022

NCBI Accession: NP_001127934

UniProt: A8MTQ0