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GUCA2B antibody (Middle Region)
GUCA2B
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-GUCA2B Antibody
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Target
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GUCA2B
(Guanylate Cyclase Activator 2B (Uroguanylin) (GUCA2B))
Binding Specificity
All epitopes for GUCA2B antibodies
Middle Region
Reactivity
All reactivities for GUCA2B antibodies
Human
Host
All hosts for GUCA2B antibodies
Rabbit
Clonality
All clonalities for GUCA2B antibodies
Polyclonal
Conjugate
All conjugates for GUCA2B antibodies
This GUCA2B antibody is un-conjugated
Application
All applications for GUCA2B antibodies
Western Blotting (WB)
Sequence
MKKLSDLEAQ WAPSPRLQAQ SLLPAVCHHP ALPQDLQPVC ASQEASSIFK
Characteristics
This is a rabbit polyclonal antibody against GUC2B. It was validated on Western Blot.
Purification
Affinity purified
Immunogen
The immunogen for Anti-GUCA2B antibody is: synthetic peptide directed towards the middle region of Human GUC2B
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for GUCA2B
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Target
GUCA2B
(Guanylate Cyclase Activator 2B (Uroguanylin) (GUCA2B))
Alternative Name
GUCA2B (GUCA2B Products )
Synonyms
GUCA2B antibody, AV066530 antibody, Gcap2 antibody, Ugn antibody, GCAP-II antibody, UGN antibody, guanylate cyclase activator 2B antibody, guanylate cyclase activator 2b (retina) antibody, GUCA2B antibody, Guca2b antibody
Background
This gene encodes a member of the guanylin family, and is expressed in the stomach and intestine. This protein functions as an endogenous ligand for the guanylate cyclase-C receptor and stimulates an increase in cyclic GMP, a key component of several intracellular signal transduction pathways. It maybe involved in salt and water secretion into the intestinal lumen as well as the renal tubules, and thus regulate electrolyte homeostasis in these tissues. Alias Symbols: UGN, GCAP-II, Protein Size: 112
Gene ID
2981
NCBI Accession
NP_009033
UniProt
Q16661
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