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DPM2 antibody (Middle Region)
DPM2
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-DPM2 Antibody
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Target
See all DPM2 Antibodies
DPM2
(Dolichyl-Phosphate Mannosyltransferase Polypeptide 2, Regulatory Subunit (DPM2))
Binding Specificity
Middle Region
Reactivity
All reactivities for DPM2 antibodies
Human
Host
All hosts for DPM2 antibodies
Rabbit
Clonality
All clonalities for DPM2 antibodies
Polyclonal
Conjugate
All conjugates for DPM2 antibodies
This DPM2 antibody is un-conjugated
Application
Western Blotting (WB)
Sequence
DSQHVIHKYF LPRAYAVAIP LAAGLLLLLF VGLFISYVML KTKRVTKKAQ
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human DPM2
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for DPM2
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Target
DPM2
(Dolichyl-Phosphate Mannosyltransferase Polypeptide 2, Regulatory Subunit (DPM2))
Alternative Name
DPM2 (DPM2 Products )
Synonyms
dpm2b antibody, dpm2a antibody, AW557993 antibody, R75484 antibody, CDG1U antibody, wu:fa99c01 antibody, zgc:112514 antibody, dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit S homeolog antibody, dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit L homeolog antibody, dolichol-phosphate (beta-D) mannosyltransferase 2 antibody, dolichyl-phosphate mannosyltransferase subunit 2, regulatory antibody, dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit antibody, dpm2.S antibody, dpm2.L antibody, Dpm2 antibody, DPM2 antibody, dpm2 antibody
Background
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1. Alias Symbols: CDG1U Protein Size: 84
Gene ID
8818
NCBI Accession
NM_003863 , NP_003854
UniProt
O94777
Pathways
Inositol Metabolic Process
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