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DPM2 antibody (Middle Region)

DPM2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5516306
  • Target See all DPM2 Antibodies
    DPM2 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 2, Regulatory Subunit (DPM2))
    Binding Specificity
    Middle Region
    Reactivity
    • 1
    • 1
    Human
    Host
    • 2
    Rabbit
    Clonality
    • 2
    Polyclonal
    Conjugate
    • 2
    This DPM2 antibody is un-conjugated
    Application
    Western Blotting (WB)
    Sequence
    DSQHVIHKYF LPRAYAVAIP LAAGLLLLLF VGLFISYVML KTKRVTKKAQ
    Purification
    Affinity purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human DPM2
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  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    DPM2 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 2, Regulatory Subunit (DPM2))
    Alternative Name
    DPM2 (DPM2 Products)
    Synonyms
    dpm2b antibody, dpm2a antibody, AW557993 antibody, R75484 antibody, CDG1U antibody, wu:fa99c01 antibody, zgc:112514 antibody, dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit S homeolog antibody, dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit L homeolog antibody, dolichol-phosphate (beta-D) mannosyltransferase 2 antibody, dolichyl-phosphate mannosyltransferase subunit 2, regulatory antibody, dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit antibody, dpm2.S antibody, dpm2.L antibody, Dpm2 antibody, DPM2 antibody, dpm2 antibody
    Background
    Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1.

    Alias Symbols: CDG1U

    Protein Size: 84
    Gene ID
    8818
    NCBI Accession
    NM_003863, NP_003854
    UniProt
    O94777
    Pathways
    Inositol Metabolic Process
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