F22329_1 antibody, DKFZp469H0334 antibody, cytochrome P450 family 4 subfamily F member 12 antibody, cytochrome P450, family 4, subfamily F, polypeptide 12 antibody, cytochrome P450 4F12 antibody, CYP4F12 antibody, CpipJ_CPIJ016853 antibody, MCYG_08150 antibody
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein likely localizes to the endoplasmic reticulum. When expressed in yeast the enzyme is capable of oxdizing arachidonic acid. It can also catalyze the epoxidation of 22:6n-3 and 22:5n-3 polyunsaturated long-chain fatty acids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Alternative splicing results in multiple transcript variants.