zgc:65824 antibody, zgc:77925 antibody, wu:fb94g06 antibody, wu:fd19a08 antibody, AP1S2 antibody, MGC:1902 antibody, MRX59 antibody, MRXS21 antibody, MRXSF antibody, SIGMA1B antibody, 1500012A13Rik antibody, AI853648 antibody, EST1 antibody, RGD1561862 antibody, AP1S1 antibody, adaptor-related protein complex 1, sigma 2 subunit antibody, adaptor related protein complex 1 sigma 2 subunit antibody, adaptor related protein complex 1 sigma 2 subunit pseudogene antibody, adaptor related protein complex 1 sigma 2 subunit S homeolog antibody, ap1s2 antibody, AP1S2 antibody, LOC737735 antibody, LOC741655 antibody, ap1s2.S antibody, Ap1s2 antibody
Background
Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family. Transcript variants encoding different isoforms have been found for this gene.