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PTS antibody (N-Term)
PTS
Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Pig, Guinea Pig, Zebrafish (Danio rerio)
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PTS Antibody
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Target
See all PTS Antibodies
PTS
(6-Pyruvoyltetrahydropterin Synthase (PTS))
Binding Specificity
All epitopes for PTS antibodies
N-Term
Reactivity
Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Pig, Guinea Pig, Zebrafish (Danio rerio)
Host
All hosts for PTS antibodies
Rabbit
Clonality
All clonalities for PTS antibodies
Polyclonal
Conjugate
All conjugates for PTS antibodies
This PTS antibody is un-conjugated
Application
All applications for PTS antibodies
Western Blotting (WB)
Sequence
SKFLSDEENL KLFGKCNNPN GHGHNYKVVV TVHGEIDPAT GMVMNLADLK
Predicted Reactivity
Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
Characteristics
This is a rabbit polyclonal antibody against PTPS. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human PTPS
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for PTS
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Target
PTS
(6-Pyruvoyltetrahydropterin Synthase (PTS))
Alternative Name
PTPS (PTS Products )
Synonyms
PTS antibody, Pts antibody, DDBDRAFT_0232952 antibody, DDB_0232952 antibody, ptps antibody, zgc:162276 antibody, PTPS antibody, 6-pyruvoyltetrahydropterin synthase antibody, 6-pyruvoyltetrahydropterin synthase L homeolog antibody, 6-pyruvoyl-tetrahydropterin synthase antibody, PTS antibody, pts.L antibody, Pts antibody, azo3118 antibody, Xfasm12_0164 antibody, HUTA_RS09790 antibody, Cyan8802_3683 antibody, ptsA antibody, NMAG_RS16995 antibody, pts antibody, DICPUDRAFT_151723 antibody
Background
The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. Alias Symbols: PTS, Protein Interaction Partner: COIL, SDCBP, LNX1, THAP10, PTS, ASB5, ASB1, WDYHV1, FXR2, UBC, SMURF1, AGO4, FNDC5, PRKG2, PBRM1, PRKDC, ATR, ATM, Protein Size: 145
Gene ID
5805
NCBI Accession
NP_000308
UniProt
Q03393
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