PTS antibody (N-Term)

Catalog No. ABIN5515752

Product Details anti-PTS Antibody

Target: PTS (6-Pyruvoyltetrahydropterin Synthase (PTS))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Pig, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTS antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SKFLSDEENL KLFGKCNNPN GHGHNYKVVV TVHGEIDPAT GMVMNLADLK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against PTPS. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PTPS

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PTS

Target: PTS (6-Pyruvoyltetrahydropterin Synthase (PTS))

Alternative Name: PTPS (PTS Products)

Background: The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia.

Alias Symbols: PTS,

Protein Interaction Partner: COIL, SDCBP, LNX1, THAP10, PTS, ASB5, ASB1, WDYHV1, FXR2, UBC, SMURF1, AGO4, FNDC5, PRKG2, PBRM1, PRKDC, ATR, ATM,

Protein Size: 145

Gene ID: 5805

NCBI Accession: NP_000308

UniProt: Q03393