KCND3 antibody, zgc:55306 antibody, wu:fi06g01 antibody, kv4.3 antibody, K(v)4.3 antibody, AW045978 antibody, Kncd3 antibody, Kv4.3 antibody, KCND3L antibody, KCND3S antibody, KSHIVB antibody, KV4.3 antibody, kcnd3-A antibody, xKv4.3 antibody, potassium voltage-gated channel subfamily D member 3 antibody, potassium voltage-gated channel, Shal-related subfamily, member 3 antibody, potassium channel, voltage gated Shal related subfamily D, member 3 antibody, potassium voltage-gated channel, Shal-related family, member 3 antibody, potassium channel, voltage gated Shal related subfamily D, member 3 L homeolog antibody, KCND3 antibody, kcnd3 antibody, Kcnd3 antibody, kcnd3.L antibody
Background
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.
Alias Symbols: KV4.3, SCA19, SCA22, BRGDA9, KCND3L, KCND3S, KSHIVB