DET1 antibody (N-Term)

Catalog No. ABIN5515416

Product Details anti-DET1 Antibody

Target: DET1

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DET1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DCRCVIVGSA AYLPDEPHPP FFEVYRNSES VTPNPRSPLE DYSLHIIDLH

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against DET1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human DET1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DET1

Target: DET1

Alternative Name: DET1 (DET1 Products)

Synonyms: 2610034H20Rik antibody, de-etiolated homolog 1 (Arabidopsis) antibody, DET1 antibody, Det1 antibody

Background: DET1 is a component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is involved in JUN ubiquitination and degradation.

Alias Symbols: -

Protein Interaction Partner: CUL4A, CUL4B, DDB1, RFWD2, HSP90AA1, DDA1, UBE2E3, PRMT5, UBE2E1, HSPA4, RBX1,

Protein Size: 561

Gene ID: 55070

NCBI Accession: NM_017996, NP_060466