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DEDD antibody (Middle Region)
DEDD
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-DEDD Antibody
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Target
See all DEDD Antibodies
DEDD
(Death Effector Domain Containing (DEDD))
Binding Specificity
All epitopes for DEDD antibodies
Middle Region
Reactivity
All reactivities for DEDD antibodies
Human
Host
All hosts for DEDD antibodies
Rabbit
Clonality
All clonalities for DEDD antibodies
Polyclonal
Conjugate
All conjugates for DEDD antibodies
This DEDD antibody is un-conjugated
Application
All applications for DEDD antibodies
Western Blotting (WB)
Sequence
PTSGPQMCSK RPARGRATLG SQRKRRKSVT PDPKEKQTCD IRLRVRAEYC
Characteristics
This is a rabbit polyclonal antibody against DEDD. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human DEDD
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for DEDD
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Target
DEDD
(Death Effector Domain Containing (DEDD))
Alternative Name
DEDD (DEDD Products )
Synonyms
CASP8IP1 antibody, DEDD1 antibody, DEFT antibody, FLDED1 antibody, Dedpro1 antibody, KE05 antibody, Deft antibody, death effector domain containing antibody, death effector domain-containing antibody, DEDD antibody, Dedd antibody
Background
This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. Alias Symbols: DEDD, DEDPRO1, DEFT, KE05, Protein Interaction Partner: APLP2, SMAD3, BATF2, SHMT1, APP, UBC, HOXD4, USP22, DEDD2, GTF3C1, CFLAR, FADD, CASP8, CASP10, CASP3, KRT18, KRT8, GTF3C3, DEDD, CCDC59, RANBP3, KHK, Protein Size: 318
Gene ID
9191
NCBI Accession
NP_127491
UniProt
O75618
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