TFB1M antibody (C-Term)

Catalog No. ABIN5515223

Product Details anti-TFB1M Antibody

Target: TFB1M (Transcription Factor B1, Mitochondrial (TFB1M))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFB1M antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SISHFKSLCD VYRKMCDEDP QLFAYNFREE LKRRKSKNEE KEEDDAENYR

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TFB1M

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TFB1M

Target: TFB1M (Transcription Factor B1, Mitochondrial (TFB1M))

Alternative Name: TFB1M (TFB1M Products)

Synonyms: CGI75 antibody, mtTFB antibody, mtTFB1 antibody, cgi75 antibody, mttfb antibody, cgi-75 antibody, mttfb1 antibody, CGI-75 antibody, AI429207 antibody, im:7151479 antibody, zgc:153625 antibody, CG42631 antibody, CG7319 antibody, Dmel\\CG42631 antibody, Dmel_CG7319 antibody, TFB1 antibody, d-TFB1M antibody, d-mtTFB1 antibody, transcription factor B1, mitochondrial antibody, transcription factor B1, mitochondrial L homeolog antibody, Mitochondrial Transcription Factor B1 antibody, TFB1M antibody, tfb1m.L antibody, tfb1m antibody, Tfb1m antibody, mtTFB1 antibody

Background: The protein encoded by this gene is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. The encoded protein also is part of the basal mitochondrial transcription complex and is necessary for mitochondrial gene expression. The methylation and transcriptional activities of this protein are independent of one another. Variations in this gene may influence the severity of aminoglycoside-induced deafness (AID).

Alias Symbols: CGI75, mtTFB, CGI-75, mtTFB1

Protein Size: 346

Gene ID: 51106

NCBI Accession: NM_016020, NP_057104

UniProt: Q8WVM0