CLCN4 antibody (N-Term)

Catalog No. ABIN5514642

This Rabbit Polyclonal antibody specifically detects CLCN4 in WB. It exhibits reactivity toward Human.

Quick Overview for CLCN4 antibody (N-Term) (ABIN5514642)

Target: CLCN4 (Chloride Channel 4 (CLCN4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLCN4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CLCN4 Antibody

Binding Specificity: N-Term

Sequence: LMDFLDEPFP DVGTYEDFHT IDWLREKSRD TDRHRKITSK SKESIWEFIK

Characteristics: This is a rabbit polyclonal antibody against CLCN4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CLCN4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CLCN4

Target: CLCN4 (Chloride Channel 4 (CLCN4))

Alternative Name: CLCN4

Background: The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins.

Alias Symbols: CLCN4,

Protein Size: 760

Gene ID: 1183

NCBI Accession: NP_001821

UniProt: P51793