TMED7-TICAM2 Readthrough (TMED7-TICAM2) (Middle Region) antibody

Catalog No. ABIN5514538

Product Details

Target: TMED7-TICAM2 Readthrough (TMED7-TICAM2)

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: Western Blotting (WB)

Sequence: AEHSNTTEGP TGKQEGAQSV EEMFEEEAEE EVFLKFVILH AEDDTDEALR

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TMED7-TICAM2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: TMED7-TICAM2 Readthrough (TMED7-TICAM2)

Alternative Name: TMED7-TICAM2 (TMED7-TICAM2 Products)

Synonyms: MyD88-4 antibody, TICAM-2 antibody, p24gamma3 antibody, TMED7-TICAM2 readthrough antibody, TMED7-TICAM2 antibody

Background: This locus represents naturally occurring read-through transcription between the neighboring transmembrane emp24 protein transport domain containing 7 (TMED7) and toll-like receptor adaptor molecule 2 (TICAM2) genes. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with the products of each individual gene. This fusion product functions to negatively regulate the adaptor MyD88-independent toll-like receptor 4 pathway.

Protein Size: 235

Gene ID: 100302736

NCBI Accession: NM_001164468, NP_001157940

UniProt: Q86XR7