RITA1 antibody (C-Term)
RITA1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
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- Target See all RITA1 products
- RITA1 (Tyrosine-Based Site-Specific Recombinase (Recombinase Triad in CMGI-2) (RITA1))
- Binding Specificity
- C-Term
- Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RITA1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- TNGPQDLRPS TSGVTFRSPL VTSRARSVSI SVPSTPRRGG ATQKPKPPWK
- Characteristics
- This is a rabbit polyclonal antibody against RITA1. It was validated on Western Blot.
- Purification
- Affinity purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human RITA1
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anti-Tyrosine-Based Site-Specific Recombinase (Recombinase Triad in CMGI-2) (RITA1) antibody
RITA1 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RITA1 (Tyrosine-Based Site-Specific Recombinase (Recombinase Triad in CMGI-2) (RITA1))
- Alternative Name
- RITA1 (RITA1 Products)
- Synonyms
- AI853657 antibody, C86297 antibody, Rita antibody, RBPJ interacting and tubulin associated 1 antibody, Rita1 antibody
- Background
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RITA1 is a tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. It shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. And it may play a role in neurogenesis.
Alias Symbols: C12orf52, RITA, PSEC0043
Protein Size: 269 - Gene ID
- 84934
- NCBI Accession
- XP_005254029
- UniProt
- Q96K30
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