PDE10A antibody (N-Term)

Catalog No. ABIN5514456

Product Details anti-PDE10A Antibody

Target: PDE10A (phosphodiesterase 10A (PDE10A))

Binding Specificity: N-Term

Reactivity: Human, Rat, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE10A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SLHPQVLDEF VSESVSAETV EKWLKRKNNK SEDESAPKEV SRYQDTNMQG

Predicted Reactivity: Dog: 93%, Horse: 93%, Human: 100%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against PDE10A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PDE10A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDE10A

Target: PDE10A (phosphodiesterase 10A (PDE10A))

Alternative Name: PDE10A (PDE10A Products)

Background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene.

Alias Symbols: PDE10A,

Protein Interaction Partner: TOP1, UBC, WDR3, CASP3,

Protein Size: 779

Gene ID: 10846

UniProt: Q9Y233

Pathways: cAMP Metabolic Process