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Treacle Protein antibody (N-Term)
TCOF
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Treacle Protein Antibody
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Target
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Treacle Protein (TCOF)
Binding Specificity
N-Term
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Application
Western Blotting (WB)
Sequence
MAEARKRREL LPLIYHHLLR AGYVRAAREV KEQSGQKCFL AQPVTLLDIY
Characteristics
This is a rabbit polyclonal antibody against TCOF. It was validated on Western Blot.
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human TCOF
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for Treacle Protein
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Target
Treacle Protein (TCOF)
Alternative Name
TCOF (TCOF Products )
Background
This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene. Alias Symbols: TCOF1, Protein Size: 1411
Gene ID
6949
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