TSEN34 antibody (C-Term)

Catalog No. ABIN5514423

Product Details anti-TSEN34 Antibody

Target: TSEN34 (tRNA Splicing Endonuclease 34 Homolog (TSEN34))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSEN34 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PRSALLVQLA TARPRPVKAR PLDWRVQSKD WPHAGRPAHE LRYSIYRDLW

Characteristics: This is a rabbit polyclonal antibody against SEN34. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SEN34

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TSEN34

Target: TSEN34 (tRNA Splicing Endonuclease 34 Homolog (TSEN34))

Alternative Name: SEN34 (TSEN34 Products)

Synonyms: LENG5 antibody, SEN34 antibody, 0610027F08Rik antibody, Leng5 antibody, PCH2C antibody, SEN34L antibody, tRNA splicing endonuclease subunit 34 antibody, tRNA splicing endonuclease 34 homolog (S. cerevisiae) antibody, Tsen34 antibody, TSEN34 antibody, tsen34 antibody

Background: This gene encodes a catalytic subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns from precursor tRNAs. The endonuclease complex is also associated with a pre-mRNA 3-prime end processing factor. A mutation in this gene results in the neurological disorder pontocerebellar hypoplasia type 2. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Alias Symbols: TSEN34, LENG5, SEN34,

Protein Interaction Partner: UBC, ARMCX3, RAB3GAP2, RAB3GAP1, GNE, BCAR1, GABPA, HNRNPD, Clp1, TSEN15, TSEN54, TSEN2,

Protein Size: 310

Gene ID: 79042

NCBI Accession: NP_076980

UniProt: Q9BSV6