Septin 12 antibody (AA 1-358)

Catalog No. ABIN530515

Product Details anti-Septin 12 Antibody

Target: Septin 12 (Sep12)

Binding Specificity: AA 1-358

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This Septin 12 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse polyclonal antibody raised against a full-length human SEPT12 protein.

Sequence: MDPLRRSPSP CLSSQPSSPS TPPCEMLGPV GIEAVLDQLK IKAMKMGFEF NIMVVGQSGL GKSTMVNTLF KSKVWKSNPP GLGVPTPQTL QLHSLTHVIE EKGVKLKLTV TDTPGFGDQI NNDNCWDPIL GYINEQYEQY LQEEILITRQ RHIPDTRVHC CVYFVPPTGH CLRPLDIEFL QRLCRTVNVV PVIARADSLT MEEREAFRRR IQQNLRTHCI DVYPQMCFDE DINDKILNSK LRDRIPFAVV GADQEHLVNG RCVLGRKTKW GIIEVENMAH CEFPLLRDLL IRSHLQDLKD ITHNIHYENY RVIRLNESHL LPRGPGWVNL APASPGQLTT PRTFKVCRGA HDDSDDEF

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: SEPT12 (AAH35619.1, 1 a.a. ~ 358 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Septin 12 antibody (ABIN530515)

Lai, Wu, Wang, Chen, Wang, Chen, Wu, Chiang, Kuo, Lin: "SEPT12-NDC1 Complexes Are Required for Mammalian Spermiogenesis." in: International journal of molecular sciences, Vol. 17, Issue 11, (2016) (PubMed).

Kuo, Chiang, Wang, Kuo, Chen, Yu, Teng, Lin, Lin: "SEPT12-microtubule complexes are required for sperm head and tail formation." in: International journal of molecular sciences, Vol. 14, Issue 11, pp. 22102-16, (2013) (PubMed).

Kuo, Lin, Chen, Wang, Chiou, Lin, Pan, Wu, Su, Hsu, Kuo: "SEPT12 mutations cause male infertility with defective sperm annulus." in: Human mutation, Vol. 33, Issue 4, pp. 710-9, (2012) (PubMed).

Lin, Wang, Chen, Kuo, Chiou, Lin, Wu, Hsu, Chiang, Kuo: "SEPTIN12 genetic variants confer susceptibility to teratozoospermia." in: PLoS ONE, Vol. 7, Issue 3, pp. e34011, (2012) (PubMed).

Target Details for Septin 12

Target: Septin 12 (Sep12)

Alternative Name: SEPT12 (Sep12 Products)

Background: Full Gene Name: septin 12
Synonyms: FLJ25410

Gene ID: 124404