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FBXW7 antibody (AA 1-627)

FBXW7 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
Catalog No. ABIN527477
  • Target See all FBXW7 Antibodies
    FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
    Binding Specificity
    • 15
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-627
    Reactivity
    • 63
    • 35
    • 32
    • 16
    • 15
    • 14
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 52
    • 12
    Mouse
    Clonality
    • 54
    • 10
    Polyclonal
    Conjugate
    • 33
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This FBXW7 antibody is un-conjugated
    Application
    • 54
    • 24
    • 15
    • 14
    • 13
    • 11
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purpose
    Mouse polyclonal antibody raised against a full-length human FBXW7 protein.
    Sequence
    MCVPRSGLIL SCICLYCGVL LPVLLPNLPF LTCLSMSTLE SVTYLPEKGL YCQRLPSSRT HGGTESLKGK NTENMGFYGT LKMIFYKMKR KLDHGSEVRS FSLGKKPCKV SEYTSTTGLV PCSATPTTFG DLRAANGQGQ QRRRITSVQP PTGLQEWLKM FQSWSGPEKL LALDELIDSC EPTQVKHMMQ VIEPQFQRDF ISLLPKELAL YVLSFLEPKD LLQAAQTCRY WRILAEDNLL WREKCKEEGI DEPLHIKRRK VIKPGFIHSP WKSAYIRQHR IDTNWRRGEL KSPKVLKGHD DHVITCLQFC GNRIVSGSDD NTLKVWSAVT GKCLRTLVGH TGGVWSSQMR DNIIISGSTD RTLKVWNAET GECIHTLYGH TSTVRCMHLH EKRVVSGSRD ATLRVWDIET GQCLHVLMGH VAAVRCVQYD GRRVVSGAYD FMVKVWDPET ETCLHTLQGH TNRVYSLQFD GIHVVSGSLD TSIRVWDVET GNCIHTLTGH QSLTSGMELK DNILVSGNAD STVKIWDIKT GQCLQTLQGP NKHQSAVTCL QFNKNFVITS SDDGTVKLWD LKTGEFIRNL VTLESGGSGG VVWRIRASNT KLVCAVGSRN GTEETKLLVL DFDVDMK
    Cross-Reactivity
    Human
    Characteristics
    Antibody reactive against mammalian transfected lysate.
    Immunogen
    FBXW7 (NP_060785.2, 1 a.a. ~ 627 a.a) full-length human protein.
    Top Product
    Discover our top product FBXW7 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Maskey, Marlin, Kim, Kim, Ong, Li, Tsiokas: "Cell cycle-dependent ubiquitylation and destruction of NDE1 by CDK5-FBW7 regulates ciliary length." in: The EMBO journal, Vol. 34, Issue 19, pp. 2424-40, (2015) (PubMed).

  • Target
    FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
    Alternative Name
    FBXW7 (FBXW7 Products)
    Synonyms
    cdc4 antibody, AGO antibody, CDC4 antibody, FBW6 antibody, FBW7 antibody, FBX30 antibody, FBXO30 antibody, FBXW6 antibody, SEL-10 antibody, SEL10 antibody, hAgo antibody, hCdc4 antibody, 1110001A17Rik antibody, Cdc4 antibody, Fbw7 antibody, Fbwd6 antibody, Fbx30 antibody, Fbxo30 antibody, Fbxw6 antibody, F-box and WD repeat domain containing 7 antibody, F-box and WD-40 domain protein 7 antibody, Fbxw7 antibody, FBXW7 antibody, fbxw7 antibody
    Background
    Full Gene Name: F-box and WD repeat domain containing 7
    Synonyms: AGO,CDC4,DKFZp686F23254,FBW6,FBW7,FBX30,FBXO30,FBXW6,FLJ16457,SEL-10,SEL10
    Gene ID
    55294
    NCBI Accession
    NM_018315
    Pathways
    Notch Signaling, EGFR Signaling Pathway
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