WRAP53 antibody (AA 62-160)

Catalog No. ABIN527367

Product Details anti-WRAP53 Antibody

Target: WRAP53 (WD Repeat Containing, Antisense To TP53 (WRAP53))

Binding Specificity: AA 62-160

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This WRAP53 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Purpose: Mouse monoclonal antibody raised against a partial recombinant WDR79.

Sequence: AVSQELREGD PVSLSTPLET EFGSPSELSP RIEEQELSEN TSLPAEEANG SLSEEEANGP ELGSGKAMED TSGEPAAEDE GDTAWNYSFS QLPRFLSGS

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: WDR79 (NP_060551.1, 62 a.a. ~ 160 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1F12

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-WRAP53 antibody (ABIN527367)

Henriksson, Rassoolzadeh, Hedström, Coucoravas, Julner, Goldstein, Imreh, Zhivotovsky, Kastan, Helleday, Farnebo: "The scaffold protein WRAP53? orchestrates the ubiquitin response critical for DNA double-strand break repair." in: Genes & development, Vol. 28, Issue 24, pp. 2726-38, (2014) (PubMed).

Target Details for WRAP53

Target: WRAP53 (WD Repeat Containing, Antisense To TP53 (WRAP53))

Alternative Name: WDR79 (WRAP53 Products)

Background: Full Gene Name: WD repeat domain 79
Synonyms: FLJ10385,WRAP53

Gene ID: 55135

NCBI Accession: NM_018081

Pathways: Telomere Maintenance