Ceramide Synthase 2 antibody (AA 1-380)

Catalog No. ABIN526190

Product Details anti-Ceramide Synthase 2 Antibody

Target: Ceramide Synthase 2 (CERS2)

Binding Specificity: AA 1-380

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Ceramide Synthase 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse monoclonal antibody raised against a full-length recombinant LASS2.

Sequence: MLQTLYDYFW WERLWLPVNL TWADLEDRDG RVYAKASDLY ITLPLALLFL IVRYFFELYV ATPLAALLNI KEKTRLRAPP NATLEHFYLT SGKQPKQVEV ELLSRQSGLS GRQVERWFRR RRNQDRPSLL KKFREASWRF TFYLIAFIAG MAVIVDKPWF YDMKKVWEGY PIQSTIPSQY WYYMIELSFY WSLLFSIASD VKRKDFKEQI IHHVATIILI SFSWFANYIR AGTLIMALHD SSDYLLESAK MFNYAGWKNT CNNIFIVFAI VFIITRLVIL PFWILHCTLV YPLELYPAFF GYYFFNSMMG VLQLLHIFWA YLILRMAHKF ITGKLVEDER SDREETESSE GEEAAAGGGA KSRPLANGHP ILNNNHRKND

Cross-Reactivity: Human

Immunogen: LASS2 (AAH01357, 1 a.a. ~ 380 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1A6

Isotype: IgM kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In ascites fluid

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Ceramide Synthase 2 antibody (ABIN526190)

Separovic, Breen, Joseph, Bielawski, Pierce, VAN Buren, Gudz: "Ceramide synthase 6 knockdown suppresses apoptosis after photodynamic therapy in human head and neck squamous carcinoma cells." in: Anticancer research, Vol. 32, Issue 3, pp. 753-60, (2012) (PubMed).

Separovic, Breen, Joseph, Bielawski, Pierce, VAN Buren, Gudz: "siRNA-mediated down-regulation of ceramide synthase 1 leads to apoptotic resistance in human head and neck squamous carcinoma cells after photodynamic therapy." in: Anticancer research, Vol. 32, Issue 7, pp. 2479-85, (2012) (PubMed).

Target Details for Ceramide Synthase 2

Target: Ceramide Synthase 2 (CERS2)

Alternative Name: LASS2 (CERS2 Products)

Synonyms: L3 antibody, LASS2 antibody, SP260 antibody, TMSG1 antibody, 0610013I17Rik antibody, AI225939 antibody, Lass2 antibody, TRH3 antibody, ceramide synthase 2 antibody, CERS2 antibody, Cers2 antibody

Background: Full Gene Name: LAG1 homolog, ceramide synthase 2
Synonyms: CerS2,FLJ10243,L3,MGC987,SP260,TMSG1

Gene ID: 29956