HEYL antibody (AA 221-327)

Catalog No. ABIN525730

Product Details anti-HEYL Antibody

Target: HEYL (Hairy/enhancer-of-Split Related with YRPW Motif-Like (HEYL))

Binding Specificity: AA 221-327

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HEYL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Purpose: Mouse monoclonal antibody raised against a partial recombinant HEYL.

Sequence: PLRRATGIIL PARRNVLPSR GASSTRRARP LERPATPVPV APSSRAARSS HIAPLLQSSS PTPPGPTGSA AYVAVPTPNS SSPGPAGRPA GAMLYHSWVS EITEIGA

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: HEYL (NP_055386, 221 a.a. ~ 327 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 4A11

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-HEYL antibody (ABIN525730)

Kuo, Jian, Li, Wan, Weng, Fang, Wu, Cheng: "Epigenetic inactivation of transforming growth factor-?1 target gene HEYL, a novel tumor suppressor, is involved in the P53-induced apoptotic pathway in hepatocellular carcinoma." in: Hepatology research : the official journal of the Japan Society of Hepatology, (2014) (PubMed).

Target Details for HEYL

Target: HEYL (Hairy/enhancer-of-Split Related with YRPW Motif-Like (HEYL))

Alternative Name: HEYL (HEYL Products)

Background: Full Gene Name: hairy/enhancer-of-split related with YRPW motif-like
Synonyms: HRT3,MGC12623,bHLHb33

Gene ID: 26508

NCBI Accession: NM_014571

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling