TRIM32 antibody (AA 105-204)

Catalog No. ABIN524889

Product Details anti-TRIM32 Antibody

Target: TRIM32 (Tripartite Motif Containing 32 (TRIM32))

Binding Specificity: AA 105-204

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TRIM32 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), RNA Interference (RNAi)

Purpose: Mouse monoclonal antibody raised against a partial recombinant TRIM32.

Sequence: RRLPRQFCRS CGLVLCEPCR EADHQPPGHC TLPVKEAAEE RRRDFGEKLT RLRELMGELQ RRKAALEGVS KDLQARYKAV LQEYGHEERR VQDELARSRK

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: TRIM32 (NP_036342, 105 a.a. ~ 204 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2E5

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-TRIM32 antibody (ABIN524889)

Lee, Kim, Kim, Lee, Kim, Sun: "Polarized and Stage-Dependent Distribution of Immunoreactivity for Novel PDZ-Binding Protein Preso1 in Adult Neurogenic Regions." in: Endocrinology and metabolism (Seoul, Korea), Vol. 29, Issue 3, pp. 349-55, (2014) (PubMed).

Zhang, Liu, Yao, Li, Xin, Lai, Bracchi-Ricard, Xu, Yen, Meng, Liu, Yang, Karmally, Liu, Zhu, Gordon, Khalili, Srinivasan, Bethea, Mo, Hu: "Nuclear factor kappa B signaling initiates early differentiation of neural stem cells." in: Stem cells (Dayton, Ohio), Vol. 30, Issue 3, pp. 510-24, (2012) (PubMed).

Nicklas, Otto, Wu, Miller, Stelzer, Wen, Kuang, Wrogemann, Patel, Ding, Schwamborn: "TRIM32 regulates skeletal muscle stem cell differentiation and is necessary for normal adult muscle regeneration." in: PLoS ONE, Vol. 7, Issue 1, pp. e30445, (2012) (PubMed).

Sato, Okumura, Kano, Kondo, Ariga, Hatakeyama: "TRIM32 promotes neural differentiation through retinoic acid receptor-mediated transcription." in: Journal of cell science, Vol. 124, Issue Pt 20, pp. 3492-502, (2011) (PubMed).

Schwamborn, Berezikov, Knoblich: "The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors." in: Cell, Vol. 136, Issue 5, pp. 913-25, (2009) (PubMed).

Target Details for TRIM32

Target: TRIM32 (Tripartite Motif Containing 32 (TRIM32))

Alternative Name: TRIM32 (TRIM32 Products)

Background: Full Gene Name: tripartite motif-containing 32
Synonyms: BBS11,HT2A,LGMD2H,TATIP

Gene ID: 22954

NCBI Accession: NM_012210

Pathways: Negative Regulation of intrinsic apoptotic Signaling