FAN1 antibody (AA 1-533)

Catalog No. ABIN524848

Product Details anti-FAN1 Antibody

Target: FAN1 (FANCD2/FANCI-Associated Nuclease 1 (FAN1))

Binding Specificity: AA 1-533

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This FAN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: Mouse polyclonal antibody raised against a full-length human MTMR15 protein.

Sequence: MSEGKPPDKK KRPRRSLSIS KNKKKASNSI ISCFNNAPPA KLACPVCSKM VPRYDLNRHL DEMCANNDFV QVDPGQVGLI NSNVSMVDLT SVTLEDVTPK KSPPPKTNLT PGQSDSAKRE VKQKISPYFK SNDVVCKNQD ELRNRSVKVI CLGSLASKLS RKYVKAKKSI DKDEEFAGSS PQSSKSTVVK SLIDNSSEIE DEDQILENSS QKENVFKCDS LKEECIPEHM VRESKIMEAE SQKATRECEK SALTPGFSDN AIMLFSPDFT LRNTLKSTSE DSLVKQECIK EVVEKREACH CEEVKMTVAS EAKIQLSDSE AKSHSSADDA SAWSNIQEAP LQDDSCLNND IPHSIPLEQG SSCNGPGQTT GHPYYLRSFL VVLKTVLENE DDMLLFDEQE KGIVTKFYQL SATGQKLYVR LFQRKLSWIK MTKLEYEEIA LDLTPVIEEL TNAGFLQTES ELQELSEVLE LLSAPELKSL AKTFHLVNPN GQKQQLVDAF LKLAKQRSVC TWGKNKPGIG AVILKRFCWL LLQ

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: MTMR15 (AAH47882.1, 1 a.a. ~ 533 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-FAN1 antibody (ABIN524848)

Sareen, Chaudhury, Adams, Sobeck: "Fanconi anemia proteins FANCD2 and FANCI exhibit different DNA damage responses during S-phase." in: Nucleic acids research, Vol. 40, Issue 17, pp. 8425-39, (2012) (PubMed).

Target Details for FAN1

Target: FAN1 (FANCD2/FANCI-Associated Nuclease 1 (FAN1))

Alternative Name: MTMR15 (FAN1 Products)

Background: Full Gene Name: myotubularin related protein 15
Synonyms: DKFZp451H236,DKFZp686K16147,KIAA1018

Gene ID: 22909

Pathways: DNA Damage Repair