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TREX1 antibody (AA 1-369)

TREX1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN524703
  • Target See all TREX1 Antibodies
    TREX1 (three Prime Repair Exonuclease 1 (TREX1))
    Binding Specificity
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-369
    Reactivity
    • 36
    • 5
    • 5
    Human
    Host
    • 29
    • 7
    Rabbit
    Clonality
    • 23
    • 13
    Polyclonal
    Conjugate
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This TREX1 antibody is un-conjugated
    Application
    • 22
    • 9
    • 7
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purpose
    Rabbit polyclonal antibody raised against a full-length human TREX1 protein.
    Sequence
    MGPGARRQGR IVQGRPEMCF CPPPTPLPPL RILTLGTHTP TPCSSPGSAA GTYPTMGSQA LPPGPMQTLI FFDMEATGLP FSQPKVTELC LLAVHRCALE SPPTSQGPPP TVPPPPRVVD KLSLCVAPGK ACSPAASEIT GLSTAVLAAH GRQCFDDNLA NLLLAFLRRQ PQPWCLVAHN GDRYDFPLLQ AELAMLGLTS ALDGAFCVDS ITALKALERA SSPSEHGPRK SYSLGSIYTR LYGQSPPDSH TAEGDVLALL SICQWRPQAL LRWVDAHARP FGTIRPMYGV TASARTKPRP SAVTTTAHLA TTRNTSPSLG ESRGTKDLPP VKDPGALSRE GLLAPLGLLA ILTLAVATLY GLSLATPGE
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Antibody reactive against mammalian transfected lysate.
    Immunogen
    TREX1 (NP_057465.1, 1 a.a. ~ 369 a.a) full-length human protein.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Tomicic, Aasland, Nikolova, Kaina, Christmann: "Human three prime exonuclease TREX1 is induced by genotoxic stress and involved in protection of glioma and melanoma cells to anticancer drugs." in: Biochimica et biophysica acta, Vol. 1833, Issue 8, pp. 1832-43, (2013) (PubMed).

    Christmann, Tomicic, Aasland, Berdelle, Kaina: "Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage." in: Nucleic acids research, Vol. 38, Issue 19, pp. 6418-32, (2010) (PubMed).

  • Target
    TREX1 (three Prime Repair Exonuclease 1 (TREX1))
    Alternative Name
    TREX1 (TREX1 Products)
    Background
    Full Gene Name: three prime repair exonuclease 1
    Synonyms: AGS1,AGS5,CRV,DKFZp434J0310,DRN3,HERNS
    Gene ID
    11277
    NCBI Accession
    NM_016381
    Pathways
    Apoptosis
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