Osteoactivin antibody (AA 104-203)

Catalog No. ABIN523856

Product Details anti-Osteoactivin Antibody

Target: Osteoactivin (GPNMB)

Binding Specificity: AA 104-203

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Osteoactivin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse monoclonal antibody raised against a partial recombinant GPNMB.

Sequence: RCQKEDANGN IVYEKNCRNE AGLSADPYVY NWTAWSEDSD GENGTGQSHH NVFPDGKPFP HHPGWRRWNF IYVFHTLGQY FQKLGRCSVR VSVNTANVTL

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: GPNMB (NP_001005340, 104 a.a. ~ 203 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1A8

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Osteoactivin antibody (ABIN523856)

Fiorentini, Bodei, Bedussi, Fragni, Bonini, Simeone, Zani, Berruti, Missale, Memo, Spano, Sigala: "GPNMB/OA protein increases the invasiveness of human metastatic prostate cancer cell lines DU145 and PC3 through MMP-2 and MMP-9 activity." in: Experimental cell research, Vol. 323, Issue 1, pp. 100-11, (2014) (PubMed).

Kompass, Agapova, Li, Kaufman, Rasmussen, Hernandez: "Bioinformatic and statistical analysis of the optic nerve head in a primate model of ocular hypertension." in: BMC neuroscience, Vol. 9, pp. 93, (2008) (PubMed).

Target Details for Osteoactivin

Target: Osteoactivin (GPNMB)

Alternative Name: GPNMB (GPNMB Products)

Synonyms: HGFIN antibody, NMB antibody, DC-HIL antibody, Dchil antibody, ipd antibody, glycoprotein nmb antibody, glycoprotein (transmembrane) nmb antibody, glycoprotein nmb L homeolog antibody, Gpnmb antibody, GPNMB antibody, gpnmb.L antibody

Background: Full Gene Name: glycoprotein (transmembrane) nmb
Synonyms: HGFIN,NMB

Gene ID: 10457

NCBI Accession: NM_001005340