PRPF4 antibody (AA 1-522)

Catalog No. ABIN522584

Product Details anti-PRPF4 Antibody

Target: PRPF4 (PRP4 Pre-mRNA Processing Factor 4 Homolog (PRPF4))

Binding Specificity: AA 1-522

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This PRPF4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: Mouse polyclonal antibody raised against a full-length human PRPF4 protein.

Sequence: MASSRASSTQ ATKTKAPDDL VAPVVKKPHI YYGSLEEKER ERLAKGESGI LGKDGLKAGI EAGNINITSG EVFEIEEHIS ERQAEVLAEF ERRKRARQIN VSTDDSEVKA CLRALGEPIT LFGEGPAERR ERLRNILSVV GTDALKKTKK DDEKSKKSKE EYQQTWYHEG PNSLKVARLW IANYSLPRAM KRLEEARLHK EIPETTRTSQ MQELHKSLRS LNNFCSQIGD DRPISYCHFS PNSKMLATAC WSGLCKLWSV PDCNLLHTLR GHNTNVGAIV FHPKSTVSLD PKDVNLASCA ADGSVKLWSL DSDEPVADIE GHTVRVARVM WHPSGRFLGT TCYDRSWRLW DLEAQEEILH QEGHSMGVYD IAFHQDGSLA GTGGLDAFGR VWDLRTGRCI MFLEGHLKEI YGINFSPNGY HIATGSGDNT CKVWDLRQRR CVYTIPAHQN LVTGVKFEPI HGNFLLTGAY DNTAKIWTHP GWSPLKTLAG HEGKVMGLDI SSDGQLIATC SYDRTFKLWM AE

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: PRPF4 (NP_004688, 1 a.a. ~ 522 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PRPF4 antibody (ABIN522584)

Adler, McCleland, Yee, Yaylaoglu, Hussain, Cosino, Quinones, Modrusan, Seshagiri, Torres, Chopra, Haley, Zhang, Blackwood, Singh, Junttila, Stephan, Liu, Pau, Fearon, Jiang, Firestein: "An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth." in: Genes & development, Vol. 28, Issue 10, pp. 1068-84, (2014) (PubMed).

Tanackovic, Ransijn, Thibault, Abou Elela, Klinck, Berson, Chabot, Rivolta: "PRPF mutations are associated with generalized defects in spliceosome formation and pre-mRNA splicing in patients with retinitis pigmentosa." in: Human molecular genetics, Vol. 20, Issue 11, pp. 2116-30, (2011) (PubMed).

Target Details for PRPF4

Target: PRPF4 (PRP4 Pre-mRNA Processing Factor 4 Homolog (PRPF4))

Alternative Name: PRPF4 (PRPF4 Products)

Background: Full Gene Name: PRP4 pre-mRNA processing factor 4 homolog (yeast)
Synonyms: HPRP4,HPRP4P,PRP4,Prp4p

Gene ID: 9128

NCBI Accession: NM_004697