ZEB1 antibody (AA 801-900)

Catalog No. ABIN520780

Product Details anti-ZEB1 Antibody

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Binding Specificity: AA 801-900

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZEB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Purpose: Mouse monoclonal antibody raised against a partial recombinant ZEB1.

Sequence: NIAIPTVTAQ LPTIVAIADQ NSVPCLRALA ANKQTILIPQ VAYTYSTTVS PAVQEPPLKV IQPNGNQDER QDTSSEGVSN VEDQNDSDST PPKKKMRKTE

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ZEB1 (NP_110378, 801 a.a. ~ 900 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 4C4

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ZEB1 antibody (ABIN520780)

Al-Khalaf, Aboussekhra: "p16(INK4A) induces senescence and inhibits EMT through microRNA-141/microRNA-146b-5p-dependent repression of AUF1." in: Molecular carcinogenesis, Vol. 56, Issue 3, pp. 985-999, (2016) (PubMed).

Hendrayani, Al-Khalaf, Aboussekhra: "The cytokine IL-6 reactivates breast stromal fibroblasts through transcription factor STAT3-dependent up-regulation of the RNA-binding protein AUF1." in: The Journal of biological chemistry, Vol. 289, Issue 45, pp. 30962-76, (2014) (PubMed).

Target Details for ZEB1

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Alternative Name: ZEB1 (ZEB1 Products)

Synonyms: ZFH/[d]EF1 antibody, kheper antibody, zeb1 antibody, zfhx1 antibody, bzp antibody, zeb antibody, tcf8 antibody, areb6 antibody, nil2a antibody, zfhep antibody, nil-2a antibody, zfhx1a antibody, nil-2-a antibody, MGC97552 antibody, TCF8 antibody, AREB6 antibody, BZP antibody, DELTAEF1 antibody, FECD6 antibody, NIL2A antibody, PPCD3 antibody, ZFHEP antibody, ZFHX1A antibody, 3110032K11Rik antibody, MEB1 antibody, Nil2 antibody, TCF-8 antibody, Tcf18 antibody, Tcf8 antibody, Tw antibody, ZEB antibody, Zfhep antibody, Zfhx1a antibody, Zfx1a antibody, Zfx1ha antibody, [delta]EF1 antibody, deltaEF1 antibody, deltaef1 antibody, fecd6 antibody, zinc finger E-box binding homeobox 1b antibody, zinc finger E-box binding homeobox 1 antibody, zinc finger E-box binding homeobox 1 S homeolog antibody, zeb1b antibody, zeb1 antibody, ZEB1 antibody, Zeb1 antibody, zeb1.S antibody

Background: Full Gene Name: zinc finger E-box binding homeobox 1
Synonyms: AREB6,BZP,DELTA-EF1,MGC133261,NIL-2-A,NIL-2A,NIL2A,TCF8,ZEB,ZFHEP,ZFHX1A

Gene ID: 6935

NCBI Accession: NM_030751

Pathways: Regulation of Muscle Cell Differentiation