RAD51 antibody (AA 1-339)

Catalog No. ABIN519604

Product Details anti-RAD51 Antibody

Target: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Binding Specificity: AA 1-339

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This RAD51 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse polyclonal antibody raised against a full-length human RAD51 protein.

Sequence: MAMQMQLEAN ADTSVEEESF GPQPISRLEQ CGINANDVKK LEEAGFHTVE AVAYAPKKEL INIKGISEAK ADKILAEAAK LVPMGFTTAT EFHQRRSEII QITTGSKELD KLLQGGIETG SITEMFGEFR TGKTQICHTL AVTCQLPIDR GGGEGKAMYI DTEGTFRPER LLAVAERYGL SGSDVLDNVA YARAFNTDHQ TQLLYQASAM MVESRYALLI VDSATALYRT DYSGRGELSA RQMHLARFLR MLLRLADEFG VAVVITNQVV AQVDGAAMFA ADPKKPIGGN IIAHASTTRL YLRKGRGETR ICKIYDSPCL PEAEAMFAIN ADGVGDAKD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: RAD51 (NP_002866.2, 1 a.a. ~ 339 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-RAD51 antibody (ABIN519604)

Lesterlin, Ball, Schermelleh, Sherratt: "RecA bundles mediate homology pairing between distant sisters during DNA break repair." in: Nature, Vol. 506, Issue 7487, pp. 249-53, (2014) (PubMed).

Jeyasekharan, Liu, Hattori, Pisupati, Jonsdottir, Rajendra, Lee, Sundaramoorthy, Schlachter, Kaminski, Ofir-Rosenfeld, Sato, Savill, Ayoub, Venkitaraman: "A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization." in: Nature structural & molecular biology, Vol. 20, Issue 10, pp. 1191-8, (2013) (PubMed).

Target Details for RAD51

Target: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Alternative Name: RAD51 (RAD51 Products)

Synonyms: BRCC5 antibody, HRAD51 antibody, HsRad51 antibody, HsT16930 antibody, MRMV2 antibody, RAD51A antibody, RECA antibody, CRAD51 antibody, wu:fb38e12 antibody, zgc:77754 antibody, RGD1563603 antibody, ATRAD51 antibody, F22D1.20 antibody, F22D1_20 antibody, RAS associated with diabetes protein 51 antibody, AV304093 antibody, Rad51a antibody, Reca antibody, brcc5 antibody, rad51 antibody, rad51a antibody, reca antibody, xrad51 antibody, RAD51 recombinase antibody, RAS associated with diabetes protein 51 antibody, RAD51 recombinase L homeolog antibody, RAD51 antibody, rad51 antibody, Rad51 antibody, rad51.L antibody

Background: Full Gene Name: RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
Synonyms: BRCC5,HRAD51,HsRad51,HsT16930,RAD51A,RECA

Gene ID: 5888

NCBI Accession: NM_002875

Pathways: DNA Damage Repair