SRGN antibody (AA 1-158)

Catalog No. ABIN519156

Product Details anti-SRGN Antibody

Target: SRGN (serglycin (SRGN))

Binding Specificity: AA 1-158

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SRGN antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse monoclonal antibody raised against a full-length recombinant SRGN.

Sequence: MMQKLLKCSR LVLALALILV LESSVQGYPT QRARYQWVRC NPDSNSANCL EEKGPMFELL PGESNKIPRL RTDLFPKTRI QDLNRIFPLS EDYSGSGFGS GSGSGSGSGS GFLTEMEQDY QLVDESDAFH DNLRSLDRNL PSDSQDLGQH GLEEDFML

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: SRGN (AAH15516, 1 a.a. ~ 158 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1D8

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-SRGN antibody (ABIN519156)

Gasimli, Hickey, Yang, Li, dela Rosa, Nairn, Kulik, Dordick, Moremen, Dalton, Linhardt: "Changes in glycosaminoglycan structure on differentiation of human embryonic stem cells towards mesoderm and endoderm lineages." in: Biochimica et biophysica acta, Vol. 1840, Issue 6, pp. 1993-2003, (2014) (PubMed).

Reine, Vuong, Jenssen, Kolset: "Serglycin secretion is part of the inflammatory response in activated primary human endothelial cells in vitro." in: Biochimica et biophysica acta, Vol. 1840, Issue 8, pp. 2498-505, (2014) (PubMed).

Li, Ong, Cao, Xiang, Shao, Ooi, Peng, Lu, Zhang, Petillo, Qin, Bao, Zheng, Chia, Iyer, Kang, Zeng, Soo, Trent, Teh, Qian: "Serglycin is a theranostic target in nasopharyngeal carcinoma that promotes metastasis." in: Cancer research, Vol. 71, Issue 8, pp. 3162-72, (2011) (PubMed).

Target Details for SRGN

Target: SRGN (serglycin (SRGN))

Alternative Name: SRGN (SRGN Products)

Background: Full Gene Name: serglycin
Synonyms: FLJ12930,MGC9289,PPG,PRG,PRG1

Gene ID: 5552

Pathways: Maintenance of Protein Location