Huntingtin antibody (AA 81-190)
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- Target See all Huntingtin (HTT) Antibodies
- Huntingtin (HTT)
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Binding Specificity
- AA 81-190
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Huntingtin antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB)
- Purpose
- Mouse monoclonal antibody raised against a partial recombinant HD.
- Sequence
- AVAEEPLHRP KKELSATKKD RVNHCLTICE NIVAQSVRNS PEFQKLLGIA MELFLLCSDD AESDVRMVAD ECLNKVIKAL MDSNLPRLQL ELYKEIKKNG APRSLRAALW
- Cross-Reactivity
- Human
- Characteristics
- Antibody Reactive Against Recombinant Protein.
- Immunogen
- HD (NP_002102, 81 a.a. ~ 190 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Clone
- 1H6
- Isotype
- IgG2a
- Top Product
- Discover our top product HTT Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- In 1x PBS, pH 7.4
- Handling Advice
- Aliquot to avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome. ..." in: The Journal of cell biology, Vol. 187, Issue 7, pp. 1083-99, (2009) (PubMed).
: "
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IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome. ..." in: The Journal of cell biology, Vol. 187, Issue 7, pp. 1083-99, (2009) (PubMed).
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- Target
- Huntingtin (HTT)
- Alternative Name
- HTT (HTT Products)
- Background
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Full Gene Name: huntingtin
Synonyms: HD,IT15 - Gene ID
- 3064
- NCBI Accession
- NM_002111
- Pathways
- PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
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