FKBP5 antibody (AA 1-457)

Catalog No. ABIN515669

Product Details anti-FKBP5 Antibody

Target: FKBP5 (FK506 Binding Protein 5 (FKBP5))

Binding Specificity: AA 1-457

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This FKBP5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse polyclonal antibody raised against a full-length human FKBP5 protein.

Sequence: MTTDEGAKNN EESPTATVAE QGEDITSKKD RGVLKIVKRV GNGEETPMIG DKVYVHYKGK LSNGKKFDSS HDRNEPFVFS LGKGQVIKAW DIGVATMKKG EICHLLCKPE YAYGSAGSLP KIPSNATLFF EIELLDFKGE DLFEDGGIIR RTKRKGEGYS NPNEGATVEI HLEGRCGGRM FDCRDVAFTV GEGEDHDIPI GIDKALEKMQ REEQCILYLG PRYGFGEAGK PKFGIEPNAE LIYEVTLKSF EKAKESWEMD TKEKLEQAAI VKEKGTVYFK GGKYMQAVIQ YGKIVSWLEM EYGLSEKESK ASESFLLAAF LNLAMCYLKL REYTKAVECC DKALGLDSAN EKGLYRRGEA QLLMNEFESA KGDFEKVLEV NPQNKAARLQ ISMCQKKAKE HNERDRRIYA NMFKKFAEQD AKEEANKAMG KKTSEGVTNE KGTDSQAMEE EKPEGHV

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: FKBP5 (NP_004108.1, 1 a.a. ~ 457 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-FKBP5 antibody (ABIN515669)

Romano, Xiao, Nakaya, DAngelillo, Chang, Jin, Hausch, Masullo, Feng, Romano, Sun: "FKBP51 employs both scaffold and isomerase functions to promote NF-?B activation in melanoma." in: Nucleic acids research, Vol. 43, Issue 14, pp. 6983-93, (2015) (PubMed).

Romano, DAngelillo, DArrigo, Staibano, Greco, Brunetti, Scalvenzi, Bisogni, Scala, Romano: "FKBP51 increases the tumour-promoter potential of TGF-beta." in: Clinical and translational medicine, Vol. 3, Issue 1, pp. 1, (2014) (PubMed).

Romano, Staibano, Greco, Brunetti, Nappo, Ilardi, Martinelli, Sorrentino, Di Pace, Mascolo, Bisogni, Scalvenzi, Alfano, Romano: "FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential." in: Cell death & disease, Vol. 4, pp. e578, (2013) (PubMed).

Target Details for FKBP5

Target: FKBP5 (FK506 Binding Protein 5 (FKBP5))

Alternative Name: FKBP5 (FKBP5 Products)

Synonyms: FKBP5 antibody, FKBP-5 antibody, AIG6 antibody, FKBP51 antibody, FKBP54 antibody, P54 antibody, PPIase antibody, Ptg-10 antibody, D17Ertd592e antibody, Dit1 antibody, si:zc263a23.8 antibody, wu:fc31g11 antibody, wu:fl87b03 antibody, zgc:64082 antibody, FK506 binding protein 5 antibody, FKBP5 antibody, fkbp5 antibody, Fkbp5 antibody

Background: Full Gene Name: FK506 binding protein 5
Synonyms: FKBP51,FKBP54,MGC111006,P54,PPIase,Ptg-10

Gene ID: 2289

NCBI Accession: NM_004117