RUNX2 antibody (AA 251-350)

Catalog No. ABIN514045

Product Details anti-RUNX2 Antibody

Target: RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

Binding Specificity: AA 251-350

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RUNX2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against a partial recombinant RUNX2.

Sequence: NPRPSLNSAP SPFNPQGQSQ ITDPRQAQSS PPWSYDQSYP SYLSQMTSPS IHSTTPLSST RGTGLPAITD VPRRISDDDT ATSDFCLWPS TLSKKSQAGA

Cross-Reactivity: Human, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: RUNX2 (NP_004339, 251 a.a. ~ 350 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 3F5

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-RUNX2 antibody (ABIN514045)

Sonomoto, Yamaoka, Kaneko, Yamagata, Sakata, Zhang, Kondo, Zenke, Sabanai, Nakayamada, Sakai, Tanaka: "Spontaneous Differentiation of Human Mesenchymal Stem Cells on Poly-Lactic-Co-Glycolic Acid Nano-Fiber Scaffold." in: PLoS ONE, Vol. 11, Issue 4, pp. e0153231, (2016) (PubMed).

Li, Zhou, Takai, Sasaki, Mezawa, Li, Wang, Yang, Wang, Matsumura, Kaneko, Yoshimura, Ogata: "Aggregatibacter actinomycetemcomitans lipopolysaccharide regulates bone sialoprotein gene transcription." in: Journal of cellular biochemistry, Vol. 113, Issue 9, pp. 2822-34, (2012) (PubMed).

Niu, Kondo, Nakazawa, Oishi, Kawasaki, Mochizuki, Yamane, Katoh: "Transcription factor Runx2 is a regulator of epithelial-mesenchymal transition and invasion in thyroid carcinomas." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 92, Issue 8, pp. 1181-90, (2012) (PubMed).

Wang, Li, Li, Yang, Sasaki, Wang, Zhou, Araki, Mezawa, Takai, Ogata: "Effects of inorganic polyphosphate on bone sialoprotein gene expression." in: Gene, Vol. 452, Issue 2, pp. 79-86, (2010) (PubMed).

Li, Sasaki, Mezawa, Wang, Li, Yang, Wang, Zhou, Araki, Matsumura, Takai, Ogata: "cAMP and fibroblast growth factor 2 regulate bone sialoprotein gene expression in human prostate cancer cells." in: Gene, Vol. 471, Issue 1-2, pp. 1-12, (2010) (PubMed).

Target Details for RUNX2

Target: RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

Alternative Name: RUNX2 (RUNX2 Products)

Synonyms: AML3 antibody, CBF-alpha-1 antibody, CBFA1 antibody, CCD antibody, CCD1 antibody, CLCD antibody, OSF-2 antibody, OSF2 antibody, PEA2aA antibody, PEBP2aA antibody, Cbf antibody, Cbfa-1 antibody, Cbfa1 antibody, LS3 antibody, Osf2 antibody, Pebp2a1 antibody, Pebpa2a antibody, runx2 antibody, RUNX2 antibody, ccd antibody, aml3 antibody, ccd1 antibody, osf2 antibody, cbfa1 antibody, pea2aa antibody, pebp2a1 antibody, pebp2a2 antibody, pebp2aa antibody, pebp2aa1 antibody, runt related transcription factor 2 antibody, runt-related transcription factor 2a antibody, runt-related transcription factor 2 antibody, runt related transcription factor 2 L homeolog antibody, RUNX2 antibody, runx2a antibody, Runx2 antibody, runx2 antibody, LOC703331 antibody, LOC100549663 antibody, runx2.L antibody

Background: Full Gene Name: runt-related transcription factor 2
Synonyms: AML3,CBFA1,CCD,CCD1,MGC120022,MGC120023,OSF2,PEA2aA,PEBP2A1,PEBP2A2,PEBP2aA,PEBP2aA1

Gene ID: 860

NCBI Accession: NM_004348